The loss was just the fifth in the past 21 games for the Astros, who had won the first two games of the series.

Jose Altuve hit a go-ahead two-run single in the sixth inning to move into second place on Houston's career hits list and the Astros beat the Colorado Rockies 5-3 on Wednesday night to win their 12th straight series.

Jose Altuve had two singles to pass Jeff Bagwell for second on Houston's career hit list, Shay Whitcomb hit his first major league home run and the Astros beat the Colorado Rockies 5-3 in Denver on Wednesday night.

Yordan Alvarez received two injections in his injured hand and will be shut down from baseball activities for "the upcoming days."

Alvarez first experienced issues with his hand in late April but stayed in the lineup. He was initially diagnosed with a muscle strain but a small fracture was discovered at the end of May.