Arachidonic acid is released from cellular membranes in response to allergens and pro-inflammatory stimuli by phospholipase Aâ‚‚. Once freed, it is metabolised through cyclooxygenase (COX), lipoxygenase ...
Leukotrienes are bioactive lipid mediators derived from arachidonic acid through the concerted action of lipoxygenase enzymes and associated proteins, orchestrating inflammatory initiation and ...
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