Hematopoietic stem cells (HSCs) have an amazing capacity to maintain and repopulate all the blood cells – from platelets to red blood cells to immune cells – for a person’s entire lifetime. This ...

American researchers have shown a previously overlooked structure could provide novel insights into the mechanisms underlying ...

Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and interferon ...

Scientists studying a hard-to-treat form of blood cancer called acute myeloid leukemia (AML) have found that a type of treatment—immunotherapy—may help change the environment where cancer cells live, ...

What do healthy bone marrow cells in children look like? For the first time, researchers have mapped this out. Scientists at the Princess Máxima Center examined nearly 91,000 individual bone marrow ...

A highly sensitive bone marrow test could double survival rates for some groups of younger adults with Acute Myeloid Leukemia (AML) by helping doctors identify if they might relapse up to three months ...

A new review details how the Runx1 and Gata2 transcription factors architect the epigenetic landscape of blood formation and ...

Anatomy explorers have charted a new path myeloid cells use to access the brain. On 3 June in Neuron, scientists led by Lindsay Hohsfield and Kim Green, both at the University of California, Irvine, ...

When a pathogen or other antigen activates a B cell, the cell begins proliferating and producing antibodies. Once the immune response resolves, most of the B cells die off, but some migrate to the ...