Two main biologic mechanisms can lead to chronic obstructive pulmonary disease (COPD) in adulthood: abnormal lung development and an increased rate of lung-function decline with age. These mechanisms ...

The role that eosinophilic chronic obstructive pulmonary disease (COPD) plays in the pathogenesis of COPD is not well understood, given the lack of evidence about the subject. A review focusing on the ...

Identifying DNA variants associated with bronchodilator responsiveness may reveal genetic pathways associated with the pathogenesis of chronic obstructive pulmonary disease and may identify novel ...

A recent study published in Frontiers in Immunology discussed how injury and abnormal repair of the airway epithelium drive chronic obstructive pulmonary disease (COPD) and asthma. Study: Mechanisms ...

Moderate to severe chronic obstructive pulmonary disease (COPD) may be an auto-immunity problem, according to researchers who studied the presence of auto-antibodies in patients with COPD and compared ...

Alternative splicing is known to play an important role in tissue development. Scientists at Brigham and Women’s Hospital have looked into the association between a chronic obstructive pulmonary ...