High-risk myelodysplastic syndrome, a bone marrow cancer that can turn into acute myeloid leukemia, is driven by stem cells that burn through an unusually large supply of one molecule: nicotinamide ...

A review paper summarizing the relationship between HPV infection in cervical cancer and intracellular gene regulation and ...

Researchers used CRISPR to remove CD33 from donor stem cells, potentially giving doctors a way to attack aggressive blood ...

The spread of cancer from a primary tumor to another place in the body, called metastasis, remains one of the greatest ...

A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations. When ...

High-risk MDS stem cells appear to have an unexpected “energy addiction,” relying far more heavily than healthy blood-forming cells on a molecule called NAD. Disrupting this energy pathway selectively ...

Prolonged immune signaling can switch from fighting cancer to helping tumors grow by triggering changes that suppress the immune attack.

“Obesity Leaves ‘Molecular Traces’ Even Before Colorectal Cancer Develops”... Mechanism of ‘Two-Phase Reprogramming’ Identified ...

Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung ...

Mount Sinai team finds that loss of p53 can also change how growth and tissue development signals are organized across a ...