Chloride channels and antiport mechanisms are pivotal for maintaining cellular ion homeostasis and regulating physiological processes such as muscle contraction, epithelial fluid transport and ...
Researchers have found that a primitive type of ion channel similar to those found in mammalian nerve cells helps bacteria resist the blast of acid they encounter in the stomach of their hosts. The ...
"Why did nature come up with such a structural plan?" ask Rockefeller University professor Roderick MacKinnon and colleagues in their Jan. 17 Nature cover article describing the three-dimensional ...
Credit: Shutterstock. NMD670 is a first-in-class small molecule inhibitor of the skeletal muscle specific chloride ion channel. The Food and Drug Administration (FDA) has granted Orphan Drug ...
Scientists identified a previously unknown chloride ion channel, which they named alkaliphile (Alka), as a taste receptor for alkaline pH. The sense of taste is among the first to come into contact ...
Aarhus, Denmark, 25 March 2025 – NMD Pharma A/S, a clinical-stage biotech company dedicated to developing novel and improved treatments for patients living with neuromuscular diseases, today announces ...
Neuromuscular disease specialist NMD Pharma A/S has been given U.S. FDA approval for a phase IIb trial of NMD-670, after demonstrating proof of mechanism for the orally-available chloride ion ...
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