COX-2 plays a pivotal role in ferroptosis during the progression of chronic liver disease, as it downregulates the Nrf2 signaling pathway, exacerbating ferroptosis, which is characterized by ferrous ...
Cyclooxygenases (COX-1 and COX-2) lie at the heart of the inflammatory cascade, catalysing the conversion of arachidonic acid into bioactive prostaglandins that mediate pain, fever and vascular ...
Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. However, research on COX-2 regulation of ferroptosis in ...
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