The risk of early-onset breast cancer, particularly luminal A and triple-negative subtypes, was higher in Black women with obesity and high leptin levels compared with White women. This research ...
Gabriel Y. Lai, Edward L. Giovannucci, Michael N. Pollak, Sarah B. Peskoe, Meir J. Stampfer, Walter C. Willett, Elizabeth A. Platz Cancer Causes & Control, Vol. 25 ...
Incidence of Kaposi sarcoma in HIV-infected patients receiving antiretroviral therapy: A prospective multicohort study from southern Africa. Background: Incidence of breast cancer is lower in ...
Microenvironmental factors originating from RAS-mutated cancer stem cells stimulated an angiogenic feedback loop with the surrounding environment causing the expression of leptin and TGF-β receptors ...
Serum markers to monitor response to zoledronic acid in patients with bone metastases from breast cancer. Background: Aromatase plays a critical role in the estrogen biosynthesis and affects body fat ...
R Kaaks, A Lukanova, S Rinaldi, C Biessy, S Söderberg, T Olsson, U-H Stenman, E Riboli, G Hallmans, P Stattin European Journal of Cancer Prevention, Vol. 12, No. 4 (August 2003), pp. 309-315 (7 pages) ...
Obesity and cancer are two major health challenges of our time, yet the link between them remains only partially understood. New research now highlights a molecular chain of events in estrogen ...
New research in The American Journal of Pathology clarifies the role of obesity in fueling breast cancer progression by identifying the leptin-SCD pathway as a key driver of metabolic and functional ...