Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while ...

MONMOUTH JUNCTION, N.J., Jan. 08, 2026 (GLOBE NEWSWIRE) -- Tris Pharma, Inc. (Tris), a commercial-stage biopharmaceutical company, today announced the acceptance of its peer-reviewed article "The ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

For decades, opioids have been the blunt instrument of modern pain care, powerful enough to quiet severe suffering yet risky ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Researchers identified the structure of an opioid receptor in the brain during active engagement with a drug molecule. The discovery could facilitate the creation of safer and more effective opioid ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was ...

Having a pill that alleviates chronic pain without adverse side effects or the risk of addiction remains an unmet pharmaceutical need for millions of people currently using traditional opioid drugs.

Brandy Schillace’s review of “Candace Pert” by Pamela Rykman (Bookshelf, Nov. 15) contains a questionable conclusion: the discovery of the mu opioid receptor in 1972 “helped launch the opioid crisis” ...

This confocal microscope image shows midbrain neurons (red) co-expressing the mu-opioid receptor (Oprm1, white) and cannabinoid receptor 1 (Cnr1, green). The interaction of these two reward pathways ...