In the pre-synapse, vesicle fusion is a crucial process for neurotransmitter release in the nervous system. Under physiological conditions, synaptotagmin-1 (Syt1) locks synaptic vesicles in a priming ...

Autism spectrum disorders (ASD) involve mild to severe impairment of social, behavioral and communication abilities. These disorders can significantly impact performance at school, in employment and ...

A new study from The Wistar Institute has found a link between the nervous system and the rapid development of neuroendocrine ...

A neurotransmitter previously thought only to calm neurons may also play a role in waking them up, according to a study published in the journal PLOS Biology, a discovery which challenges the textbook ...

Neurotransmitter receptors and ligands play a fundamental role in chemical signaling throughout the nervous system by ...

Neurons perform numerous complex tasks by communicating with each other via small messenger molecules called neurotransmitters. Accurately detecting them is crucial to understanding the functioning of ...

Researchers have developed a new method of labeling naïve neurotransmitter receptor proteins in living animal brains. The work is published in the journal Proceedings of the National Academy of ...

Scientists at St. Jude Children’s Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal ...

Neurotransmitter transporters are integral membrane proteins responsible for the rapid clearance of signalling molecules from the synaptic cleft and their return to presynaptic terminals.

In the world's largest study on psychedelics and the brain, a team of researchers have shown how drug-induced changes in subjective awareness are anatomically rooted in specific neurotransmitter ...