Diet is among the most important factors contributing to intestinal homeostasis, and basic functions performed by the small intestine need to be tightly preserved to maintain health. Little is known ...
Figure 1: PPAR-γ antagonism promotes ex vivo expansion of human cord blood HSPCs. Figure 3: PPAR-γ antagonism promotes ex vivo expansion of human cord blood HSCs by switching on FBP1-repressed ...
Researchers are exploring a novel quintuple agonist that targets five pathways, including GLP-1R, GIPR, and three PPARs. This innovative approach combines the benefits of incretin and PPAR pathways, ...
Chronic myeloid leukemia (CML) is a myeloproliferative disease that occurs because of a translocation between chromosomes 9 and 22 in hematopoietic stem cells. The switch results in a fusion of the ...
Natural killer T (NKT) cells maintain the immune system's balance between destruction and tolerance, a mechanism that is off kilter in autoimmune diseases such as type 1 diabetes and irritable bowel ...
The metabolic syndrome is by now unequivocally established in the minds of endocrinologists as a common and burgeoning disease linked to premature atherosclerosis and cardiovascular disease. Many ...
(Feb. 15, 2010) - In a study that could lead to new therapeutic targets for patients with the cystic fibrosis, a research team from the University of California, San Diego School of Medicine has ...
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