Artificial intelligence to speed diagnosis, switching complement therapies, ravulizumab during pregnancy, and iptacopan ...

Insights from ASH 2025, including anticipated presentations, key takeaways, and how emerging research in paroxysmal nocturnal ...

PAT is a type of arrhythmia characterized by a sudden, rapid heartbeat originating in the upper chambers of the heart, with the heart rate potentially reaching up to 250 bpm. While the exact cause of ...

Paroxysmal nocturnal hemoglobinuria (PNH) means that red blood cells break down before they should. This can lead to chronic, highly individual effects that often include bloody urine, anemia, and ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder that causes red blood cells to break down. This can lead to symptoms and complications ranging from discoloration of urine to leukemia and ...

Benign means it's not very serious. Your life is not in danger. Paroxysmal means that it hits suddenly, lasts a short time, and comes and goes. Positional means you trigger the vertigo with certain ...

PND usually occurs several hours after a person falls asleep and improves when they sit upright. This difficulty in breathing can cause a person to wake up gasping for air. It can be a distressing ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, severe, and potentially life-threatening condition. Treatments targeting the complement pathway have revolutionized its management but have ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disease in which the immune system breaks apart the red blood cells (RBCs) in the body. The medical term for this premature rupture of RBCs is ...

Figure 1: Clonal expansion in paroxysmal nocturnal haemoglobinuria. The term PNH was introduced by J. Enneking in 1928 (Ref. 4). In 1937, Thomas Ham observed that erythrocytes from patients with PNH ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disease in which changes in stem cells within the bone marrow prompt red blood cells to break apart. This deprives the body of the normal flow ...