NFL Week 17 kicks off Thursday, but latest Christmas Day tripleheader features only one certain playoff team and not much drama. Our picks

Jacksonville is only 1-6 in its last seven games in Indianapolis. Fortunately for coach Liam Coen’s team, the Jaguars are changing a lot of trends in a positive way. Jacksonville has a top-five defense over the past four weeks and a notable special-teams edge in this matchup. That’s why I’m picking the Jaguars to win and cover.

Like it or not, MVP is always a QB award. That won’t change, even in a down year. Guys like Drake Maye and Trevor Lawrence will have their time in the future, but when it comes to this season the choice is easy. Matthew Stafford is your MVP.

The games are played all the same, and I pick a side for every Week 17 matchup in my ATS NFL picks below. The Commanders allowed 22 second-half points in their 11-point loss to the Eagles last week, and while the Cowboys are reeling, I trust their offense as much as any unit on the field in this game.

As a holiday treat, here's The Tennessean's first 2026 NFL mock draft, with the Tennessee Titans picking sixth overall. QBs Fernando Mendoza and Dante Moore go early.

DFS millionaire Mike McClure shares his top daily fantasy picks and lineup advice for Indianapolis vs. San Francisco on 'Monday Night Football'