For decades, drug hunters have largely ignored the oily interior of the cell membrane, treating the membrane-spanning ...

Combining ribosome profiling, cryo-electron tomography and photocrosslinking, researchers have revealed how the ER membrane ...

Scientists at Scripps Research have engineered a synthetic protein capable of binding to Toll-like receptor 4 within the cell ...

To sense their environment and respond accordingly, cells enlist membrane proteins as communication hubs, receiving molecular ...

Membrane receptors and transporters translate extracellular cues into cellular responses by harnessing conformational changes, ion flux or enzymatic activity. Fast-acting ligand-gated ion channels ...

Mining millions of AI-predicted structures reveals an evolutionarily conserved protein that resembles a receptor family member but functions differently. Read the paper: TM184C is a GPCR-like ...

A cell sitting in fluid looks like one of the most passive things in biology. Nutrients drift toward it on the aimless ...

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), ...

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), ...

Many pharmacy students likely find that even though they are grouped together as "receptors," the types are divided into G protein-coupled, ion channel-linked, and enzyme-linked, making their ...

Hello, I'm Scat.Last time, we thought about the state and quality of cells, starting from the question of what a "good cell" ...