Overdiagnosis of sepsis and delayed optimization of antibiotics may reduce sepsis pathway effectiveness, according to researchers in Australia. “Although early antibiotic therapy is likely to reduce ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

Philadelphia-based Penn Medicine is working to reduce sepsis readmissions and improve life after sepsis for survivors with a new post-discharge care pathway. Mark Mikkelsen, MD, chief of medical ...

Professors Yao Yongming and Du Xiaohui, leading a research group at the Chinese PLA General Hospital, have published groundbreaking findings demonstrating that CD4+ T lymphocytes undergo PANoptosis ...

A key immune response pathway regulated by zinc has been discovered by scientists that may hold clues to stopping sepsis, one of the leading causes of death in America’s intensive care units. As many ...

Sepsis, a deadly overreaction of the immune system to infection, has befuddled clinicians and researchers for decades. Covid-19 made things worse. The early signs and symptoms of sepsis mimic those of ...

Sepsis, a form of systemic inflammation, is the leading cause of death in critically ill patients. Now, a new study finds that inhibition of a specific cell death pathway called "necroptosis" ...

Sepsis is the hosts’ excessive response to an infection, causing a systemic inflammatory response. Its pathophysiology is complex, depending on several molecular pathways leading to cytokine release, ...

Sepsis is the body's extreme response to an infection. It affects approximately 1.7 million adults in the United States each year and potentially contributes to more than 250,000 deaths. When ...