Dr. Jason Smith, University of Louisville Hospital's chief medical officer, said doctors who treated victims dealt with a "spectrum of injuries" consistent with an explosion, including blast injuries, thermal injuries and injuries from falling debris.

Beshear addressed the explosion that struck Louisville on Thursday, saying his primary focus is on the deceased victims.

Residents across Louisville reported around 3 p.m. feeling the explosion, which occurred at Givaudan Sense Colour at 1901 Payne St.

Louisville firefighters pulled a victim from the rubble of an industrial explosion overnight Wednesday, right after midnight. Another died at UofL Hospital after being injured in the afternoon explosion at Givaudan Sense Colour,

"When you're dealing with a large explosion like this, and such a massive amount of destruction, it's going to be difficult," one official said.

Kentucky’s governor says investigators will find out what caused a deadly explosion that ripped apart a Louisville factory

Video showed a partially collapsed and burned industrial building after an explosion at a factory in Louisville, Kentucky, killed at least two people and injured several others on Nov. 12, manufacturer Givaudan said in an emailed statement.

Two people were killed and a dozen were injured Tuesday in an explosion involving hazardous materials at a Louisville factory.