Neuroscientist Roya Huang tells us about their experience of publishing in the eLife Model. Roya Huang is a Postdoctoral Fellow in the Department of Molecular and Cell Biology, University of ...

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up ...

eLife reviews plant biology research including development, epigenetics, genomics, signalling, metabolism and plant-microbe interactions. Learn more about what we review and sign up for the latest ...

eLife reviews research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we review and sign up for the latest research.

eLife has changed its editorial process to eliminate accept/reject decisions after peer review and instead provide readers with richer and more nuanced assessments of articles. eLife changed its ...

Crystal structures of γ-protocadherin cell-cell recognition dimers reveal the determinants of clustered protocadherin homophilic specificity and cis interaction region structures alongside mutagenesis ...

Cryo-EM structures of 70S•RelA ribosome complexes reveal how cognate deacyl-tRNA activates RelA.

The Sox8 gene is capable of triggering female mice to develop male physical characteristics. In humans, mice and other mammals, genetic sex is determined by the combination of sex chromosomes that ...

Cryo-electron tomography, reconstitution, and electrophysiological data show that a fundamental function of Munc13-1 is to bridge synaptic vesicles to the presynaptic plasma membrane.

The structure of the calcium channel Orai in an open conformation reveals a dilated pore and gives insight into mechanisms of ion permeation and calcium selectivity.

To control reaching, the nervous system must generate large changes in muscle activation to drive the limb toward the target, and must also make smaller adjustments for precise and accurate behavior.

Osteoporosis most often treated by reducing bone resorption as there are limited choices of medication that are anabolic for bone. Previous studies have suggested that the Notch signaling pathway ...