How the brain protects itself from Alzheimer’s disease: Yale study

High levels of calcium are toxic to cells and contribute to loss of neurons in Alzheimer’s disease. A new JCI Insight study ...
eLife

PKD2L1 channels segregated to the apical compartment are the exclusive dual-mode pH sensor in cerebrospinal fluid-contacting neurons

This is an important study on the sensory roles of Cerebrospinal fluid-contacting neurons (CBF-cn) in mammals. The authors identify PKD2L1 as the predominant pH-sensing channel CBF-cn and show how the ...

Researchers reveal high-fat diet-induced dysfunction in brain's lateral septum that exacerbates obesity

The prevalence of overweight and obesity is largely driven by the widespread availability of high-calorie and highly ...
eLife

Pallium-encoded valence-specific chemosensory amplification of eye-body coordination in larval zebrafish

Coordinated eye-body movements are essential for adaptive behavior, yet little is known about how multisensory input, particularly chemosensory cues, shapes this coordination. Using our enhanced ...