Researchers have identified a conserved small GTPase complex that acts as a molecular gate controlling regulated secretion in ...
Researchers have discovered that Giardia lamblia runs an ATG8-independent autophagy-like pathway regulated by its sole Rho ...
Data showed improvements in an objective measure of impaired eye movement associated with Parkinson’s disease, with a correlation between ...
Arvinas, Inc. (Nasdaq: ARVN), a clinical-stage biotechnology company creating a new class of drugs based on targeted protein degradation, today announced that novel biomarker data from a Phase 1 ...
生活里职场持续内卷、长期人际冲突，不同人展现出截然不同的压力应对结果。这种抗压能力差异背后，大脑内部的分子层面发生了哪些改变？ 2026年9月24日，德国美因茨约翰内斯·古滕贝格大学医学中心Susanne Gerber、Jennifer Winter教授团队在《Molecular Psychiatry》上发表研究“Multi-omics characterization of chronic so ...
Months after reported negotiations fell off between Merck and Revolution Medicines, the pharma has instead entered a licensing deal with China-based ...
Cedars-Sinai Health Sciences University investigators have identified a drug-like compound that prevents two proteins from working together to promote the growth of colorectal and liver cancer.
Adlai Nortye Biopharma Co. Ltd. and Adlai Nortye Pte Ltd. have divulged GTPase KRAS (mutant) inhibitors reported to be useful for the treatment of cancer, inflammatory diseases and immunological ...
Cell migration underpins embryonic development, immune surveillance and the dissemination of cancer cells. At its core lies a dynamic interplay between the actin cytoskeleton and a family of small ...
Small guanosine triphosphatases (GTPases) act as molecular switches that orchestrate the rapid assembly of defence machinery in plants. Members of the Rho, Rac/ROP and Rab families cycle between an ...
This is a fundamental discovery revealing two independent IFNγ-induced pathways that restrict bacterial motility: one GBP1-dependent and the other GVIN1-dependent. The findings are supported by ...
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