New research shows carboplatin drives the expansion of TP53-mutant blood clones far more strongly than PARP inhibitors, while ...

A new conditional knockout mouse model shows that loss of the epigenetic regulator Tet2, combined with aging and a reshaped ...

Nagase and colleagues recently described a mouse model of CHIP and its transformation to a model of acute myeloid leukemia. 5 An Asxl1 mutation causes CHIP (Panel A) and leads to epigenetic ...

Share on Pinterest A cellular process that affects blood cells emerges as a new risk factor for atherosclerosis. Image credit: Mangkelin/Getty Images. Their two recent studies have uncovered new ...

A research team led by Professor Megumu K. Saito (Department of Clinical Application) examined the dynamic transcriptional and epigenetic landscape during definitive hematopoiesis and revealed the non ...

The decrease in the incidence of cardiovascular disease and the improved prognosis in persons with a diagnosis of cardiovascular disease are due, in part, to the development of new treatments based on ...

Explains how blood is produced inside your bones, focusing on the role of bone marrow and the basics of hematopoiesis. #blood ...

Phase I Dose-Escalation Study of Once Weekly or Once Every Two Weeks Administration of High-Dose Sunitinib in Patients With Refractory Solid Tumors The article by Boettcher et al entitled “Clonal ...

The immune system is one of the most complex and fascinating networks in the human body. Comprised of cellular and humoral components, it not only protects us against external intruders such as ...

To the known risk factors for cardiovascular disease - high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity - a new one has to be added: clonal ...