Recently, spatial omics has become a powerful tool, enabling researchers to see not only what molecules are present in a ...

An Oxford-developed single-allele chromatin mapping platform called MCCv identifies causal noncoding variants in autoimmune ...

A single-cell atlas of alternative polyadenylation across two million human brain cells reveals a hidden genetic regulatory ...

The W.M. Keck Foundation has awarded $1.3 million to the University of California San Diego to support an ambitious research project to map the complex three-dimensional structures formed by RNA ...

Circadian rhythms influence not only sleep and metabolism but also the ability of cancer cells to invade, survive in blood, ...

RNA-seq analysis converts sequencing reads into quantified expression measurements and statistically supported claims about which genes differ between conditions. The pipeline appears algorithmic, but ...

A molecular atlas of 89,494 mouse spinal neurons revealed 14 distinct groups within V1 interneurons, cells involved in coordinating movement. Loss of one small V1 subgroup was associated with slower ...

C.H. Waddington’s powerful image of embryonic stem cells specializing on a rolling landscape has captivated biologists since the 1950s. Experimental data is finally confirming, and complicating, his ...

Epidemiological studies link light at night (LAN), shift work, chronic jet lag (CJL), and core clock gene mutations to higher cancer risk and aggressive spread, especially in breast and colorectal ...

Using genome editing to trace cell lineages, researchers capture the early history of the mouse embryo in unprecedented ...

Gene-editing technologies enabled researchers to trace the cell-by-cell development of a single fertilised mouse egg to a ...