George Kittle could have to miss his first game of the season as the San Francisco 49ers take on the Los Angeles Rams on ...

San Francisco 49ers quarterback Brock Purdy is still making quite an impact in the state of Iowa despite being three years ...

The 49ers woes in Minnesota continued last week when their former quarterback Sam Darnold torched his old squad. The offense ...

NFL Week 3 odds, picks, predictions, TV and streaming information for the Sunday football game between the San Francisco ...

In June, Jefferson signed a record-setting deal with Minnesota. The four-year, $140 million contract extension made Jefferson ...

San Francisco 49ers left tackle Trent Williams said he wants to play until he's 40 years old, per NFL on CBS. More News: Jets ...

Do we have a revenge game on our hands in NFL Week 2? Sam Darnold – the San Francisco 49ers backup quarterback last season – ...

The 49ers and Vikings had two of the Top 5 most impressive wins during Week 1 of the NFL season, but only one can come away 2 ...

Sam Darnold passed for 268 yards and two touchdowns against his former team, including a 97-yard strike in the second quarter ...

A recent proposal from 49ers reporter Matt Barrows of The Athletic suggests a potential trade that could send running back ...

Christian McCaffrey didn't play, but the 49ers didn't skip a beat when they crushed the New York Jets on "Monday Night ...

The retirement of Aaron Donald has shifted the landscape, pushing both the 49ers and Rams to adapt their strategies for an ...