British Journal of Ophthalmology

Intra-arterial melphalan for the treatment of high-grade uveal lymphoma

High-grade lymphoma with uveal involvement is a rare cancer with poor visual and survival prognosis. We describe our ...
British Journal of Ophthalmology

Statin use is associated with lower risk of open-angle glaucoma incidence and treatment escalation

Background Retrospective cohort study using the TriNetX database to explore the relationship between statin use and glaucoma.
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Reversal of optic disc cupping in primary congenital glaucoma: analysis of 1223 eyes

Background/Aims To determine the prevalence and predictors of postoperative optic disc cupping reversal in primary congenital glaucoma (PCG). Methods This retrospective chart review included 1223 eyes ...
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Evaluation of globe-preserving therapies in unilateral cT2/cT3 retinoblastoma: a multicentre study of 1566 eyes

1 State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Aims To evaluate survival, globe ...
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Corneal radius-specific axial length/corneal radius ratio cut-offs for improved myopia detection in children: a population-based study

1 Clinical Research Center, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, School of Medicine, Tongji University, Shanghai Engineering Research Center of Precise ...
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Association of fenofibrate use with progression of ocular disease in individuals with diabetes

Background/aims Fenofibrates may slow progression of diabetic retinopathy (DR). This study used the large international TriNetX database to evaluate progression of retinopathy and development of ...
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Semaglutide-associated NAION: a proposed ‘two-hit’ model involving buried optic disc drusen and sustained hypohydration

Semaglutide-associated non-arteritic anterior ischaemic optic neuropathy (NAION) mechanisms are unclear. We report a 28-year-old man with type 2 diabetes who developed right NAION 4–5 months after ...
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Safe use of fluorinated gases in vitreoretinal surgery: learning from patient safety incidents with expert panel recommendations from the British and Eire Association of ...

Background Errors in intravitreal fluorinated gas selection or dilution can result in unintended expansile concentrations, causing irreversible visual loss. We aimed to quantify the problem using ...
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Identifying patients with poor visual outcomes after primary rhegmatogenous retinal detachment surgery using machine learning

Aims To develop prediction models for identifying cases with poor visual outcomes after surgery for primary rhegmatogenous retinal detachment (RRD). Methods All data were obtained from the ...
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Reference map of multimodal vision deficits in intermediate age-related macular degeneration: contrast sensitivity and low-contrast visual acuity

Purpose To provide a reference map of deficits in contrast sensitivity (CS) and low-contrast visual acuity (LCVA) across stages of non-exudative age-related macular degeneration (AMD) and evaluate ...
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Drusen volume and reticular pseudodrusen volume from optical coherence tomography with deep learning as risk factors for progression to late age-related macular degeneration in ...

Aim To implement a deep learning-based segmentation algorithm to quantify reticular pseudodrusen (RPD) and drusen volumes on optical coherence tomography (OCT) and investigate their association with ...
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Choroidal vascular hyperpermeability and submacular haemorrhage in polypoidal choroidal vasculopathy: a multi-field ICGA analysis

Purpose To investigate the association between choroidal vascular hyperpermeability (CVH) and the occurrence of submacular haemorrhage (SMH) in polypoidal choroidal vasculopathy (PCV). Methods This ...