There are effective approaches for 2D segmentation, yet 3D cell segmentation remains a critical bottleneck due to diverse cell morphologies, low signal-to-noise ratios, and data scarcity. We introduce ...

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest ...

Add a comment + Open annotations. The current annotation count on this page is being calculated. A large-scale study of 88 bird species reveals that some birds with high blood sugar levels show ...

This important study indicates a role for linker Histone H1 in protecting heterochromatic regions from certain types of repression. The experiments and data analysis that support the model for the ...

This important study explores the interplay between Legionella Dot/Icm effectors that modulate ubiquitination of the host GTPase Rab10, which undergoes phosphoribosyl-ubiquitination by the SidE family ...

Open annotations (there are currently 0 annotations on this page). On January 31 2023, we launched our new model for publishing, combining the speed and transparency of preprints with the expert ...

This work advances on two Aso et al 2014 eLife papers to describe further resources that are valuable for the field. This paper identified and contributes additional MBON split-Gal4s, convincingly ...

Zebrafish have an impressive capacity to regenerate neurons in the central nervous system. However, regeneration of the principal neuron of the evolutionary conserved cerebellum, the Purkinje cell (PC ...

Reactive oxygen species (ROS) accumulation is a cardinal feature of skeletal muscle atrophy. ROS refers to a collection of radical molecules whose cellular signals are vast, and it is unclear which ...