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Two simple molecules can react to form most of the intermediates in an analog of the modern-day Krebs cycle, without the need for enzymes or metals, according to a new study (Nat. Chem. 2020, DOI: ...

In the intricate dance of cellular development, metabolic pathways are far from mere background players; they are vital orchestrators that remodel and redefine the very identity of a cell. Recent ...

Scientists led by a team at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out how a molecular machine found in mitochondria—the “powerhouses” of ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

L'acide pyruvique ou pyruvate provient de la dégradation du glucose par l'organisme. Pourquoi faire un dosage et quels sont les résultats possibles ? Le pyruvate est aussi produit lors de la ...

While intraocular pressure (IOP) lowering therapy can slow or halt glaucoma, some patients continue to lose vision despite adequate IOP reduction. In a phase 2 clinical trial, nicotinamide and ...

Pyrukynd (mitapivat) is a prescription drug that’s used to treat hemolytic anemia. Pyrukynd comes as an oral tablet. Pyrukynd is used to treat hemolytic anemia in adults who have pyruvate kinase (PK) ...

Glucose has long been considered the primary fuel source for the brain. However, glucose levels fluctuate in the brain during sleep or circuit activity, posing major metabolic stress. Here, we ...

四川大学余达刚团队报道了可见光光催化下三元C（sp 3 ）-H键与CO 2 的直接羧化反应——全碳四元羧酸的简易合成。相关研究成果于2024年10月7日发表在《美国化学会杂志》。 C-H键与CO 2 的直接羧 ...

An article in Protein & Cell discusses the multifactorial nature of obesity, highlighting its association with chronic low-grade inflammation, or meta-inflammation, which contributes to metabolic ...