Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. "This is the first detailed study ...

The effects of disease-associated genetic variants on gene expression and genome accessibility have been analysed together.

A new review argues that transcription occurs in multi-scale bursts shaped by DNA methylation, histone variants, ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

An international team of researchers has assembled one of the largest single-cell genetic atlases ever built, profiling more ...

Understanding human biology requires more than mapping our genes—we must also understand how gene expression is regulated to guide healthy development, growth, and maintenance of our body systems over ...

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. Alternative splicing—the way cells edit gene messages—forms a second, independent layer of ...

Researchers have identified patterns of gene activity associated with severe COVID-19 in children that are shared with other ...

Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they ...

Understanding human biology requires more than mapping our genes – we must also understand how gene expression is regulated to guide healthy development, growth, and maintenance of our body systems ...