The former University of Minnesota standout and Eden Prairie-native has been all over the field, leading the team in tackles ...

Quarterback Brock Purdy saw a tough day on the field, grappling with multiple turnovers and getting sacked six times. This ...

Despite Cowing's setback, the 49ers showed remarkable resilience throughout the game. Shortly after the muffed punt, ...

National Football League odds courtesy of BetMGM. Odds updated Thursday at 5:41 PM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub. The 229 passing yards ...

Although the famed Rams-49ers rivalry has been decidedly tilted in San Francisco’s direction in recent years, the games have ...

San Francisco 49ers quarterback Brock Purdy is still making quite an impact in the state of Iowa despite being three years ...

Brock Purdy hasn't been quite the same since he lost to the Baltimore Ravens on Christmas. Heading into the game, he was the overwhelming favorite to win the MV ...

The decision to place quarterback Tua Tagovailoa on injured reserve gives all parties something that's very hard to come by ...

San Francisco 49ers running back Christian McCaffrey will practice on Wednesday, though he will once again be limited.

29. Indianapolis Colts (0-2) – They knew the Packers were going to run the ball and could not do anything about it. They gave up 260 yards in one game! 28. Jacksonville Jaguars (0-2) – Trevor Lawrence ...

The San Francisco 49ers will be without receiver Deebo Samuel and running back Christian McCaffrey when they take on the Los ...

Colts quarterback Anthony Richardson took the shotgun snap in Week 1, dropped back and slipped. He steadied his back leg, ...