If Notre Dame is going to win the game the offense will need to step up and be at its best. USC is a much improved defensive football team under coordinator D'Anton Lynn. The battle between Lynn and Notre Dame offensive coordinator Mike Denbrock is going to have a big say in who wins this football game.

What to watch for as Notre Dame visits USC in this college football rivalry matchup, with our updated prediction for the game.

Our Notre Dame vs USC prop picks have a trio of rushing prop picks for you to sink your teeth into. The No. 5 Notre Dame Fighting Irish look to stay in the thick of the College Football Playoff hunt as they head west to face the rival USC Trojans in the regular season finale.