All six of the NFL teams playing on Thanksgiving will be without critical players. The Chicago Bears will be without center Ryan Bates (concussion). The Detroit Lions will be without cornerback Carlton Davis III (knee/thumb) and left tackle Taylor Decker (knee).

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in the fold?

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there is growing concern about the long-term status of left tackle Trent Williams.

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an injury to his throwing shoulder.

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle Shanahan announced that

San Francisco 49ers head coach Kyle Shanahan told reporters that star quarterback Brock Purdy will practice with the team today.

The San Francisco 49ers are reportedly hoping that quarterback Brock Purdy's shoulder injury isn't a long-term issue, but there's still some