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  1. Rhabdomyolysis: Clinical manifestations and diagnosis - UpToDate

    Sep 23, 2024 · Creatine kinase elevation — The hallmark of rhabdomyolysis is an elevation in CK and other serum muscle enzymes indicative of muscle injury (eg, aldolase, aminotransferases, lactate …

  2. Drug-induced myopathies - UpToDate

    Apr 22, 2024 · Occasionally, patients may present with isolated elevation of the creatine kinase (CK) level without symptoms. PATHOGENESIS Drug-induced myopathy may result from several different …

  3. Use of creatine kinase to detect myocardial injury - UpToDate

    Sep 29, 2023 · Creatine kinase (CK) and its MB isoenzyme (CK-MB) were the most commonly used serologic tests for the diagnosis of myocardial infarction prior to the widespread adoption of troponin.

  4. Rhabdomyolysis: Epidemiology and etiology - UpToDate

    Sep 3, 2025 · The severity of illness ranges from asymptomatic elevations in serum muscle enzymes to life-threatening disease associated with extreme enzyme elevations, electrolyte imbalances, and …

  5. Neuroleptic malignant syndrome - UpToDate

    Aug 7, 2025 · Comprehensive resource on neuroleptic malignant syndrome, covering causes, symptoms, diagnosis, treatment, and prevention of this potentially life-threatening condition.

  6. Medline ® Abstract for Reference 123 of 'Daptomycin: An overview'

    A Kaplan-Meier curve was used to evaluate time to CPK elevation. Cox regression analyses were used to compare the risk of developing elevated CPK between 3 study groups: those receiving daptomycin …

  7. Rhabdomyolysis: Clinical manifestations and diagnosis

    Creatine kinase elevation — The hallmark of rhabdomyolysis is an elevation in CK and other serum muscle enzymes indicative of muscle injury (eg, aldolase, aminotransferases, lactate dehydrogenase).

  8. Medline ® Abstract for Reference 113 of 'Daptomycin: An overview'

    Although risk factors for daptomycin-associated myopathy are poorly defined, creatine phosphokinase (CPK) monitoring and temporary discontinuation of 3-hydroxy-3-methylglutaryl coenzyme A …

  9. Serum enzymes in patients with kidney failure - UpToDate

    Dec 13, 2023 · Since the diagnosis of many diseases is based upon the detection of elevated levels of these enzymes, the accurate clinical assessment of the patient with ESKD is hampered by a paucity …

  10. Hypothyroid myopathy - UpToDate

    Serum creatine kinase (CK) and other muscle enzymes are often elevated in these infants. The electromyogram (EMG) may be normal or show scattered low-amplitude motor unit potentials in …