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We break down the concepts of preload and afterload using a simple water balloon analogy. I explain that preload is the amount of fluid filling the heart before it pumps (the fill), while afterload is the resistance the heart must overcome to push blood out (the fight). We discuss what increases and decreases each—preload increases with IV fluids and kidney failure, decreases with hemorrhage and diuretics, while afterload increases with vasoconstriction and high blood pressure, and decreases wit
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