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A study published November 30, 2025 in the Journal of Neurology, Neurosurgery & Psychiatry found that weight loss in Parkinson’s disease may be driven primarily by fat loss — not muscle loss. Researchers identified reductions in glycolysis and Krebs cycle intermediates, suggesting impaired glucose metabolism and a compensatory shift toward fat breakdown and ketone production. Translation? This isn’t just “eating less.” It’s metabolic. Parkinson’s is not just a dopamine disorder. It’s systemic. I
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